Anti-Vascular Endothelial Growth Factor Receptor 2 (KDR), Human Antibody
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产品名称: Anti-Vascular Endothelial Growth Factor Receptor 2 (KDR), Human Antibody
产品型号: Y105237
产品展商: 其他品牌
产品文档: 无相关文档
简单介绍
Anti-Vascular Endothelial Growth Factor Receptor 2 (KDR), Human Antibody
Anti-Vascular Endothelial Growth Factor Receptor 2 (KDR), Human Antibody
的详细介绍
| Overview |
Print Version
|
| Product Name |
Anti-Vascular Endothelial Growth Factor Receptor 2 (KDR), Human Antibody |
| Description |
Rabbit polyclonal to VEGF Receptor 2.
VEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as s for SH2 and phosphotyrosine binding containing signalling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
|
| Subtype |
polyclonal |
| Application |
IHC |
| Raised In |
Rabbit |
| Immunogen |
Synthetic peptide - KLH conjugated. |
| Guarantee |
abm guarantees that all our Anti-Vascular Endothelial Growth Factor Receptor 2 (KDR), Human Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Properties |
|
| Formulation |
Liquid |
| Quantity |
50 μg |
| Clone |
Polyclonal Antibody |
| Storage |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Purity |
Affinity purified |
| Species Reactivity |
Human |
| Specific References |
|
Y105237 has not yet been referenced specifically in any publications.
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