Anti-Epidermal Growth Factor (EGF) Antibody
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产品名称: Anti-Epidermal Growth Factor (EGF) Antibody
产品型号: Y104157
产品展商: 其他品牌
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简单介绍
Anti-Epidermal Growth Factor (EGF) Antibody
Anti-Epidermal Growth Factor (EGF) Antibody
的详细介绍
| Overview |
Print Version
|
| Product Name |
Anti-Epidermal Growth Factor (EGF) Antibody |
| Description |
Epidermal growth factor (EGF) has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide. EGF exerts its actions by binding to the EGFR, a 170 kDa protein.
Epidermal growth factor (EGF) is a key growth factor regulating cell survival. Through its binding to cell surface receptors, EGF activates an extensive network of signal transduction pathways that include activation of the PI3K/AKT, RAS/ERK and JAK/STAT pathways. Because of its key role in driving the proliferation of cells, EGFR is a target of several anti-cancer drugs currently in development. Epidermal Growth Factor antibody clone number M0110281 |
| Subtype |
monoclonal |
| Application |
other |
| Raised In |
mouse |
| Immunogen |
Highly pure human Epidermal Growth Factor |
| Guarantee |
abm guarantees that all our Anti-Epidermal Growth Factor (EGF) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Properties |
|
| Formulation |
Liquid |
| Quantity |
500 μg |
| Clone |
Monoclonal |
| Storage |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Storage Buffer |
PBS buffer, pH 7.3 with 0.1% sodium azide. |
| Purity |
Affinity purified |
| Isotype |
IgG1 |
| Species Reactivity |
human |
| Specific References |
|
Y104157 has not yet been referenced specifically in any publications.
|
