Anti-rh FGF Basic (Fibroblast Growth Factor-Basic) Antibody
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产品名称: Anti-rh FGF Basic (Fibroblast Growth Factor-Basic) Antibody
产品型号: Y075079
产品展商: 其他品牌
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简单介绍
Anti-rh FGF Basic (Fibroblast Growth Factor-Basic) Antibody
Anti-rh FGF Basic (Fibroblast Growth Factor-Basic) Antibody
的详细介绍
| Overview |
Print Version
|
| Product Name |
Anti-rh FGF Basic (Fibroblast Growth Factor-Basic) Antibody |
| Description |
Fibroblast growth factors (FGFs), a heparin binding growth factor, exhibit widespread mitogenic and neurotrophic activities in a variety of different cells including mesenchymal, neuroectodermal and endothelial cells. aFGF (FGF-1) and bFGF (FGF-2) are present in relatively high levels in CNS. aFGF is expressed by a subset of neuronal populations, while bFGF is expressed by astrocytes, both lack signal peptides. Human bFGF is a 17.2 kDa protein containing 155 amino acid residues. FUNCTION: The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. SUBUNIT: Monomer. Interacts with CSPG4 and FGFBP1. Found in a complex with FGFBP1, FGF1 and FGF2. MISCELLANEOUS: This protein binds heparin more strongly than does aFGF. SIMILARITY: Belongs to the heparin-binding growth factors family. |
| Subtype |
polyclonal |
| Application |
WB,IHC |
| Raised In |
sheep |
| Specificity |
A high level of specificity for bFGF was shown by immunohistochemistry for this antiserum. |
| Immunogen |
Recombinant human basic FGF |
| Guarantee |
abm guarantees that all our Anti-rh FGF Basic (Fibroblast Growth Factor-Basic) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Properties |
|
| Formulation |
Liquid |
| Quantity |
100 μl |
| Storage |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Storage Buffer |
PBS, pH 7.4 with 0.02% sodium azide. |
| Concentration |
1µg/ul |
| Purity |
Filter purified |
| Species Reactivity |
human,mouse,rat |
| Specific References |
|
Y075079 has been referenced in 1 publication.
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1. Abraham, et al. (1986) Science. 233(4763):545-8
2. Kurokawa, et al. (1987) FEBS Lett. 213(1):189-94
3. Bieger, et al., (1995) J Neurochem 64, 1521-7
4. Takayama, et al., (1995)Nat Med 1, 53-8.
5. Eckenstein (1994) J Neurobiol 25, 1467-80. (1994)
6. Abraham, et al., (1986) Embo J 5, 2523-8
7. English, et al., (1995)Dev Biol 169, 57-64.
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