Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody
如果您对该产品感兴趣的话,可以
产品名称: Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody
产品型号: Y050566
产品展商: 其他品牌
产品文档: 无相关文档
简单介绍
Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody
Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody
的详细介绍
| Overview |
Print Version
|
| Product Name |
Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody |
| Description |
GRB7(Growth factor receptor-bound protein 7) is a potential signal transduction molecule, and a variant of human Grb7 which is associated with invasive esophageal carcinoma. GRB7 interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediated by the SH2 domain. GRB7 also binds to ERBB2 and interacts with RND1. GRB7 belongs to the GRB7/10/14 family and contains 1 PH domain, 1 Ras-associating domain and 1 SH2 domain. |
| Subtype |
polyclonal |
| Application |
WB, ELISA |
| Raised In |
rabbit |
| Immunogen |
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human Growth factor receptor-bound protein 7 (GRB7 adapter protein) or Epidermal growth factor receptor GRB-7 (B47). |
| Guarantee |
abm guarantees that all our Anti-GRB7(Growth factor receptor-bound protein 7)-(C-terminal) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Properties |
|
| Formulation |
Liquid |
| Quantity |
100 μg |
| Clone |
Polyclonal |
| Storage |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Storage Buffer |
PBS, pH 7.4 with 0.05% sodium azide. |
| Concentration |
1µg/ul |
| Purity |
Purified by antigen-specific affinity chromatography. |
| Isotype |
IgG |
| Species Reactivity |
human |
| Specific References |
|
Y050566 has been referenced in 1 publication.
-
Kishi,T., et al, Biochem. Biophys. Res. Commun. 232 (1), 5-9 (1997)
Tanaka,S., et al, J. Clin. Invest. 102 (4), 821-827 (1998)
Tanaka,S., et al, Cancer Res. 57 (1), 28-31 (1997)
Vayssiere,B., et al, FEBS Lett. 467 (1), 91-96 (2000)
|
