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产品名称: mMYC Purified Protein
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简单介绍
mMYC Purified Protein
mMYC Purified Protein
的详细介绍
|
Print Version |
| Organism |
Mouse |
| Accession # |
P01108 |
| Alias |
c-Myc |
| Protein Type |
Wild Type |
| Protein Sequence |
MPLNVNFTNRNYDLDYDSVQPYFICDEEENFYHQQQQSELQPPAPSEDIWKKFELLPAPPLSPSRRSGLCSPSYVAVATSFSPREDDDGGGGNFSTADQLEMMTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSTSLSPARGHSVCSTSSLYLQDLTAAASECIDPSVVFPYPLNDSSSPKSCTSSDSTAFSPSSDSLLSSESSPRASPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQTPAKRSESGSSPSRGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRAKLDSGRVLKQISNNRKCSSPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSIQADEHKLTSEKDLLRKRREQLKHKLEQLRNSGA |
| Protein Family |
Not Specified. |
| Functions |
Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes. Myc is one of the four factors in the Yamanaka protocol for iPSC reprogramming. The recombinant protein within the lysate has a 6X His tag at N-terminus for purification and 9X Arginine at C-terminus for cell membrane penetration. |
| Cell Types |
Expressed in the proliferating cells of the developing CNS and the epidermis. |
| Protein Location |
Nucleus. |
| Tag |
6X His tag at N-terminus and 9X Poly-Arginine at C-terminus |
| Form |
Liquid |
| Expression System |
E.coli |
| Type |
Purified Protein |
| Purification |
Affinity Chromatography |
| Quality Control |
By Western Blot Analysis |
| Concentration |
250ug/ml |
| Storage |
PBS |
| Shipping |
On dry ice. |
| Notes |
For Research Use Only, not for therapeutic or diagnostic purposes. |
| References |
Induction of pluripotent stem cells from ***** human fibroblasts by defined factors. Takahashi et al. Cell. 2007 Nov 30;131(5):861-72.
Induction of pluripotent stem cells from mouse embryonic and ***** fibroblast cultures by defined factors. Takahaski and Yamanaka. Cell. 2006 Aug 25;126(4):663-76. Epub 2006 Aug 10. |
