Anti-Myc (Ab-373) Antibody
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产品名称: Anti-Myc (Ab-373) Antibody
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简单介绍
Anti-Myc (Ab-373) Antibody
的详细介绍
| Overview |
Print Version
|
| Product Name |
Anti-Myc (Ab-373) Antibody |
| Description |
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008] |
| Subtype |
polyclonal |
| Application |
WB |
| Raised In |
rabbit |
| Specificity |
Myc (Ab-373) antibody detects endogenous levels of total Myc protein. |
| Immunogen |
The antiserum was produced against synthesized non-phosphopeptide derived from human
Myc around the phosphorylation site of serine 373 (K-R-SP-F-F). |
| Guarantee |
abm guarantees that all our Anti-Myc (Ab-373) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Properties |
|
| Formulation |
Liquid |
| Quantity |
100 μg |
| Clone |
N/A |
| Storage |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Storage Buffer |
phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration |
1µg/ul |
| Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using
epitope-specific immunogen. |
| Species Reactivity |
human, mouse, rat |
| Anti-Myc (Ab-373) Antibody Images |
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| Specific References |
|
Y021036 has been referenced in 1 publication.
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Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702.
Blackwood E M, et al. (1991) Science. 251:1211-1217.
Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182.
Grandori C, et al. (2000) Annu Rev Cell Dev Biol. 16: 653-699.
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