11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) Antibody
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产品名称: 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) Antibody
产品型号: abx001363
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简单介绍
11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) Antibody
11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) Antibody
的详细介绍
HSD11B1 Antibody is a Rabbit Polyclonal antibody against HSD11B1. The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.
| Target |
HSD11B1 |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human HSD11B1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 32 kDa
Observed MW: 32 kDa |
| Swiss Prot |
P28845
|
| GeneID |
3290
|
| Gene Symbol |
HSD11B1 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
