FITC - anti human CD21 - Clone HI21a
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产品名称: FITC - anti human CD21 - Clone HI21a
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简单介绍
FITC - anti human CD21 - Clone HI21a
FITC - anti human CD21 - Clone HI21a
的详细介绍
FITC
- anti Human
CD21 - HI21a
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HI21a
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IgG2a
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FCM
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FITC
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Please refer to the Certificate of Analysis for the lot-specific concentration.
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Tissue / cell preparation (Human).
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Human
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The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
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IVD-CE
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CD21, clone HI21a is a mAb intended for identification/enumeration of mature B cells, follicular dendritic cells and epithelial cells by FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
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Store in the dark at 2-8 °C
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This antibody reacts with the CD21-antigen, which reacts with the C3d complement fragment and with Epstein Barr virus (EBV) receptors, found on mature B cells, follicular dendritic cells, andsome epithelial cells. It is also weakly expressed on a subset of mature T cells and thymocytes.
This clone also cross-reacts with a major subset of, but not all, peripheral blood CD20 + lymphocytes of baboon, and both rhesus and cynomolgus macaque monkeys. A subset of CD3 + cells is also CD21 +. The monoclonal antibody is directed against the CD21-antigen, which is expressed on normal Ig-positive B-cells from peripheral blood and lymphoid tissues and on dendritic cells of germinal centres. Its expression is lost on activated B-cells. The distinct distribution among B-cell malignancies differs from other B-cell markers e.g. CD19 and CD20
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Complement receptor type 2 (Cr2), Complement C3d receptor, Epstein-Barr virus receptor (EBV receptor), C3DR
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1380
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145 kDa
