PURE - anti human CD22 - Clone HIB22
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产品名称: PURE - anti human CD22 - Clone HIB22
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PURE - anti human CD22 - Clone HIB22
PURE - anti human CD22 - Clone HIB22
的详细介绍
PURE
- anti Human
CD22 - HIB22
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HIB22
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IgG1
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FCM
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PURE
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Please refer to the Certificate of Analysis for the lot-specific concentration.
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Hairy Cell Leukemia cells
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Human
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The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
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RUO
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CD22, clone HIB22 is a mAb intended for identification/enumeration of B cells subsets, so much mature as late pro- and early pre-B cells by FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
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Store in the dark at 2-8 °C
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This antibody reacts with the CD22-antigen, which is expressed on human B lymphocytes. CD22 is expressed in the cytoplasm of virtually all B cells except plasma cells. CD45RO antigen on T cells and CD75 antigen on B cells have been identified as ligands for CD22. CD22 has been reported to participate in B-cell activation and also as an adhesion molecule. Although the immunobiology of this antigen has not been fully elucidated, reports indicate that ligation of CD22 induces constitutive internalization of the molecule followed by complete degradation.
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B-cell receptor CD22, B-lymphocyte cell adhesion molecule (BL-CAM), Sialic acid-binding Ig-like lectin 2 (Siglec-2), T-cell surface antigen Leu-14, SIGLEC-2, SIGLEC2, Lyb8
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933
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130 - 140 kDa
