FITC - anti human CD41 - Clone HIP8
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产品名称: FITC - anti human CD41 - Clone HIP8
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简单介绍
FITC - anti human CD41 - Clone HIP8
FITC - anti human CD41 - Clone HIP8
的详细介绍
FITC
- anti Human
CD41 - HIP8
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HIP8
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IgG1
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FCM
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FITC
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Please refer to the Certificate of Analysis for the lot-specific concentration.
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Purified platelet membrane glycoproteins
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Human
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The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
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IVD-CE
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CD41, clone HIP8 is a mAb intended for identification/ enumeration of GPIIb protein expressed on platelets and megakaryocytes using FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
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This antibody reacts with the CD41-antigen, which recognises the intact platelet gpIIb/IIIa complex; it does not bind to dissociated gpIIb or gpIIIa only to gpIIb in the intact complex. This is found on platelets, megakaryocytes and monocytes. The antibody does not bind to platelets from patients with Glanzmann Thrombasthenia and does not recognize the vitronectin receptor, which contains gpIIa as a beta subunit. The monoclonal antibody activates human thrombocytes and induces thrombocyte aggregation in the absence of thrombocyte inhibitors such as EDTA.
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Integrin alpha-IIb, GPalpha IIb, GPIIb, Platelet membrane glycoprotein Iib
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3674
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25 kDa
