PE - anti human CD42b - Clone HIP1
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产品名称: PE - anti human CD42b - Clone HIP1
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简单介绍
PE - anti human CD42b - Clone HIP1
PE - anti human CD42b - Clone HIP1
的详细介绍
PE
- anti Human
CD42b - HIP1
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HIP1
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IgG1
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FCM
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PE
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Please refer to the Certificate of Analysis for the lot-specific concentration.
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Tissue / cell preparation (Human). Peripheral blood mononuclear cells of a patient suffering with CLL.
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Human
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The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
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RUO
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CD42b, clone HIP1 is a mAb intended for the identification/enumeration of platelets, thrombocytes and megakaryocytes using FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
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This antibody reacts with the CD42b-antigen. It reacts with a two chain membrane glycoprotein, GpIb, that forms a non covalent complex with GPIX (CD42a) found on platelets and magakaryocytes. Clone HIP1 antibody inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets, ristocetin-induced platelet agglutination and partially inhibits collagen induced aggregation. The GPIb/IX complex serves as the vWF surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls.
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Glycocalicin, gpIb?
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2812
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17-22kDa
