PURE - anti human CD45RC - Clone RP1/12
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产品名称: PURE - anti human CD45RC - Clone RP1/12
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PURE - anti human CD45RC - Clone RP1/12
PURE - anti human CD45RC - Clone RP1/12
的详细介绍
PURE
- anti Human
CD45RC - RP1/12
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RP1/12
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IgG1
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FCM
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PURE
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Please refer to the Certificate of Analysis for the lot-specific concentration.
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Cells CD45+ of healtly donors
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Human
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The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
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RUO
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CD45RC, clone RPI/12 is a mAb intended for the identification/enumeration of pre-B lymphocytes, B cells using FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
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This antibody reacts with CD45RC on pre-B lymphocytes, B cells, CD8+ T suppressor/cytotoxic cells and a subset of CD4+ T helper (Th) lymphocytes. It weakly reacts with thymocytes.
Levels of expression of CD45RC have also been reported to distinguish resting from activated T cells at various stages of maturation. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.
CD45RC subsets within the CD4 and CD8 T cell compartments exhibit different cytokine profiles, and that their relative proportion is variable from one individual to another.
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B220, CD45R, CD45RA, CD45RB, CD45RC, CD45RO, EC 3.1.3.4, LCA, T200, Ly5, Leukocyte common antigen, L-CA
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220?kDa
