PE - anti human CD45RO - Clone UCHL1
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产品名称: PE - anti human CD45RO - Clone UCHL1
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简单介绍
PE - anti human CD45RO - Clone UCHL1
PE - anti human CD45RO - Clone UCHL1
的详细介绍
PE
- anti Human
CD45RO - UCHL1
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UCHL1
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IgG2a
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FCM
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PE
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Please refer to the Certificate of Analysis for the lot-specific concentration.
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Human IL-2-dependent T-cell line
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Human
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The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
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RUO
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CD45RO, clone UCHL1 is a mAb intended for identification/enumeration of CD45RO present on approx. 40% of peripheral blood T lymph using FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
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This antibody reacts with the CD45RO antigen, which is present at low density early in the T-lymphocyte maturation cycle. Upon activation by phytohemagglutinin (PHA) or alloantigen, naive T lymphocytes first acquire CD45RO and then lose CD45RA. When these activated T lymphocytes are rechallenged, the cells that exhibit a secondary response are primarily CD45RO +, leading to the concept that CD45RO + cells are a primed population of memory T lymphocytes.
In peripheral blood, the CD45RO antigen is present on approximately 40% of resting peripheral blood T lymphocytes, including the CD4 + and CD8 + subpopulations, as well as on most thymocytes and activated T lymphocytes. It is also expressed on monocytes, macrophages, and granulocytes
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Restricted T201
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220?kDa
