PURE - anti human CD56 - Clone B-A19
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产品名称: PURE - anti human CD56 - Clone B-A19
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PURE - anti human CD56 - Clone B-A19
PURE - anti human CD56 - Clone B-A19
的详细介绍
PURE
- anti Human
CD56 - B-A19
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B-A19
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IgG1
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FCM
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PURE
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Please refer to the Certificate of Analysis for the lot-specific concentration.
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U937 cell line (Human)
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Human
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The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
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RUO
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CD56, clone B-A19, is a mAb valid for identification of Natural Killer (NK) Cells and a subpopulation of T lymphocytes. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
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This antibody reacts with the CD56-antigen, which is expressed in lymphocytes mediating non-MHC restricted cytotoxicity and is present on some neural tissues and tumors. It is expressed on natural killer (NK) Cells and a subpopulation of T lymphocytes. NK cells make up approximately 10-25% of peripheral blood lymphocytes.
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Expression of neural cell adhesion molecules (N-CAM) provides neurons with a means of attaching to and interacting with other cells and the extracellular matrix. There are describes 6 isoforms produced by alternative splicing of N-CAM mRNA. The three major isoforms are referred to as 180 kD, 140 kD, and 120 kD. Individual isoforms undergo various post-translational modifications, including the addition of polysialic acid residues to embryonic forms. The highly polysialylated forms of N-CAM present in embryos and neonates are lost during maturation and replaced by less-polysialic acid-laden mature forms of N-CAM. The functional significance of alternative forms of N-CAM remain to be fully elucidated.
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Leu-19, NKH1, NCAM, CAMPATH-1 antige, CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, Human epididymis-specific protein 5, He6
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4684
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175-185kDa
