PE - anti human CD56 - Clone MEM-188
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产品名称: PE - anti human CD56 - Clone MEM-188
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简单介绍
PE - anti human CD56 - Clone MEM-188
PE - anti human CD56 - Clone MEM-188
的详细介绍
PE
- anti Human
CD56 - MEM-188
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MEM-188
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IgG1
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FCM
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PE
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Please refer to the Certificate of Analysis for the lot-specific concentration.
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KG-1 human acute myelogenous leukemia cell line
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Human
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The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
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RUO
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CD56, clone MEM-118, is a mAb valid for identification of Natural Killer (NK) Cells and a subpopulation of T lymphocytes. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
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This antibody reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.
CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.
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Leu-19, NKH1, NCAM, CAMPATH-1 antige, CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, Human epididymis-specific protein 5, He13
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4684
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175-185kDa
