PE - anti human CD59 - Clone MEM-43
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产品名称: PE - anti human CD59 - Clone MEM-43
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简单介绍
PE - anti human CD59 - Clone MEM-43
PE - anti human CD59 - Clone MEM-43
的详细介绍
PE
- anti Human
CD59 - MEM-43
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MEM-43
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IgG1
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FCM
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PE
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Please refer to the Certificate of Analysis for the lot-specific concentration.
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Thymocytes and T lymphocytes.
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Human
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The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
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RUO
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CD59, clone MEM-43, is a mAb used for the idenfitication of CD59 protein expressed on all hematopoietic cells. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
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This antibody reacts with the CD59-antigen, a PI-linked glycoprotein, molecular weight 18-20kDa, found in all types of leukocytes including platelets. Antigen distribution is to be found across many hemopoietic and non-hemopoietic cells. CD59 inhibits formation of membrane attack complex (MAC), thus protecting cells from complement mediated lysis Has a signaling role, as a GPI-anchored molecule, in T cell activation. Appears to have some role in cell adhesion through CD2 (controversial).
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1F-5Ag, H19, HRF20, MACIF, MIRL, P-18, PROTECTIN, Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, EC-2.4.1.135, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA
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966
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18-20kDa
