LDLR
chaperone MESD, Mesoderm development candidate 2, Mesoderm development protein,
Mesdc2, Mesd.
Mesoderm development candidate 2 (MESDC2) is required for formation of the primitive streak and mesoderm during embryogenesis. MESDC2 binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression.
MESDC2 Mouse Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 218 amino acids (30-224 a.a) and
having a molecular mass of 24.4kDa.
MESDC2 is fused to a 23 amino acid His-tag
at N-terminus & purified by proprietary chromatographic techniques.
Escherichia Coli.
Sterile Filtered colorless solution.
MESDC2
protein solution (1mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10%
glycerol.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Greater
than 90.0% as determined by SDS-PAGE.
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
