NAPG Human

Gamma-soluble NSF attachment protein, SNAP-gamma, N-ethylmaleimide-sensitive factor attachment protein gamma, NAPG, SNAPG, GAMMASNAP.

Gamma-SNAP (NAPG) is a cytoplasmic protein which binds to a membrane receptor complex composed of VAMP, SNAP25 and syntaxin. NAPG mediates the membrane binding of NSF, which is crucial for membrane fusion reactions. NSF and SNAPs seem to be general components of the intracellular membrane fusion system, and their action at specific sites of fusion needs be controlled by SNAP receptors specific to the membranes being fused. NAPG mediates platelet exocytosis and controls the membrane fusion events of this process.

NAPG Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 336 amino acids (1-312 a.a.) and having a molecular mass of 37.3kDa.
NAPG is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Escherichia Coli.

Sterile Filtered colorless solution.

NAPG protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.1M NaCl and 1mM DTT.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.

Greater than 95.0% as determined by SDS-PAGE.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.