Catalogue number
PRO-2152
Synonyms
Septin 3, SEP3, Neuronal-Specific Septin 3, Neuronal-Specific
Septin-3, BK250D10.3, Neuronal-specific septin-3.
Introduction
Septin-3, also known as SEPT3 is a member of the septin family of
GTPases. Members of this family are essential for cytokinesis. Furthermore, expression
is up regulated by retinoic acid in a human teratocarcinoma cell line. The exact
role of SEPT3 has not been determined yet. In addition, among its related
pathways are Bacterial invasion of epithelial cells.
Description
SEPT3 Human Recombinant produced in E.Coli is a single, non-glycosylated
polypeptide chain containing 381 amino acids (1-358 a.a) and having a molecular
mass of 43.1kDa.
SEPT3 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
SEPT3 protein solution (1mg/ml) containing Phosphate
buffered saline (pH7.4), 10% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSMSKGLPE TRTDAAMSEL VPEPRPKPAV PMKPMSINSN LLGYIGIDTI
IEQMRKKTMK TGFDFNIMVV GQSGLGKSTL VNTLFKSQVS RKASSWNREE KIPKTVEIKA IGHVIEEGGV
KMKLTVIDTP GFGDQINNEN CWEPIEKYIN EQYEKFLKEE
VNIARKKRIP DTRVHCCLYF ISPTGHSLRP LDLEFMKHLS KVVNIIPVIA
KADTMTLEEK SEFKQRVRKE LEVNGIEFYP QKEFDEDLED KTENDKIRQE SMPFAVVGSD KEYQVNGKRV
LGRKTPWGII EVENLNHCEF ALLRDFVIRT HLQDLKEVTH NIHYETYRAK RLNDNGGLPP
GEGLLGTVLP PVPATPCPTA E.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
