Catalogue number
ANT-041
Synonyms
GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy.
Type
Polyclonal Rabbit
Antibody.
Introduction
GDF8 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and ***** tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
Immunogen
r.Human Myostatin
Ig Subclass
Rabbit IgG
Antigen Amino Acid Sequence
HHHHHHDFGL DCDEHSTESR CCRYPLTVDF EAFGWDWIIA PKRYKANYCS GECEFVFLQK
YPHTHLVHQA NPRGSAGPCC TPTKMSPINM LYFNGKEQII YGKIPAMVVD RCGCS
Purification Method
Purified IgG prepared by affinity chromatography on protein G.
Formulation
Lyophilized from 1mg/ml solution in 0.2µm sterile filtered solution in phosphate buffered saline.
Solubility
Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Stability
Store at 4°C. For long term storage freezes in working aliquots at -20°C.
Repeated freezing and thawing is not recommended.
Purity
Greater than 98.0% as determined by Analysis by SDS-PAGE.
Applications
To detect Human Myostatin by WB analysis this IgG can be used in a dilution of 1/500.
To optimal usage we suggest overnight incubation.
Safety Data Sheet
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
