Mouse anti Dengue virus prM protein antibody – clone CC5

This Mouse anti Dengue virus prM protein antibody is specific for the prM protein of Dengue virus, biding to prM from all 4 serotypes.

The antibody binds both to native Dengue viruses, and to recombinant Dengue virus-like particles.  In Western Blotting the antibody binds less strongly to Dengue Serotype 4 than to other serotypes.  However, in ELISA and Immunofluorescence the antibody binds strongly to all 4 serotypes.

With more than one-third of the world’s population living in areas at risk of transmission, dengue infection is a leading cause of illness and death in the tropics and subtropics (ref WHO for Guidelines for Diagnosis, Treatment, Prevention & Control, 2009) As many as 100 million people are infected yearly. Dengue is caused by any one of four related viruses transmitted by mosquitoes. There are no vaccines available to prevent infection with dengue virus.

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