For Research Use Only. Not for use in diagnostic procedures.

Human serum immunochemically depleted of C6 protein.

Quidel's depleted sera are specifically depleted of a single complement protein. With the exception of the depleted protein, the alternative and classical pathways are left intact. These reagents are therefore ideal for the detection and quantitation of hemolytically active complement components.

Depleted sera have been used to assess complement activation in non-human species. For a copy of the monograph "Quantitation of C3 activity in Murine Sera by Hemolytic Assay" contact Quidel Technical Support.

References

T. Sato, Mieneke, G. The terminal Sequence of complement plays an essential role in Antibody mediated renal cell apoptosis, J Am Soc Nephrol 10:1242-1252, 1999.

C. Koski, Dashell, S. Sublytic terminal complement complex decreases Po gene expression in schwan cells, J Neurochem 73(6):2321-2330. 1999.