ABL (pY393 / 412) Antibody
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产品名称: ABL (pY393 / 412) Antibody
产品型号: abx011620
产品展商: 其他品牌
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简单介绍
ABL (pY393 / 412) Antibody
的详细介绍
Phospho-ABL (Tyr393/412) Antibody detects endogenous levels of ABL only when phosphorylated at Tyrosine 393/412. The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-ABL protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene.
Target |
ABL (pY393/412) |
Reactivity |
Human, Mouse |
Host |
Rabbit |
Clonality |
Polyclonal |
Tested Applications |
WB |
Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
Purification |
Purified by affinity chromatography. |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
Swiss Prot |
P00519
P42684
|
Gene Symbol |
ABL1, ABL2 |
Enzyme Commission Number |
EC 2.7.10.2 |
Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |