ADAM Metallopeptidase With Thrombospondin Type 1 Motif 4 (ADAMTS4) Antibody
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产品名称: ADAM Metallopeptidase With Thrombospondin Type 1 Motif 4 (ADAMTS4) Antibody
产品型号: abx001965
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简单介绍
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 4 (ADAMTS4) Antibody
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 4 (ADAMTS4) Antibody
的详细介绍
ADAMTS4 Antibody is a Rabbit Polyclonal antibody against ADAMTS4. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
| Target |
ADAMTS4 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human ADAMTS4. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 90 kDa
Observed MW: 90 kDa |
| Swiss Prot |
O75173
|
| GeneID |
9507
|
| Gene Symbol |
ADAMTS4 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
