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产品名称: AKT2 (pS474) Antibody
产品型号: abx000353
产品展商: 其他品牌
产品文档: 无相关文档
简单介绍
AKT2 (pS474) Antibody
的详细介绍
AKT2 (pS474) Antibody is a Rabbit Polyclonal antibody against AKT2 (pS474). This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
| Target |
AKT2 (pS474) |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC |
| Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S474 of human AKT2. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 51 kDa/55 kDa
Observed MW: 56 kDa |
| Swiss Prot |
P31751
|
| GeneID |
208
|
| Gene Symbol |
AKT2 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
