Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) Antibody
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产品名称: Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) Antibody
产品型号: abx025612
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简单介绍
Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) Antibody
Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) Antibody
的详细介绍
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
| Target |
AKR1C3 |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, FCM |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Human AKR1C3. |
| Purification |
Peptide Affinity Purified Rabbit Polyclonal Antibody. |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Specificity |
This AKR1C3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-36 amino acids from the N-terminal region of human AKR1C3. |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P42330
|
| Gene Symbol |
AKR1C3 |
| Buffer |
PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
