Anthrax Toxin Receptor 1 (ANTXR1) Antibody
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产品名称: Anthrax Toxin Receptor 1 (ANTXR1) Antibody
产品型号: abx005005
产品展商: 其他品牌
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简单介绍
Anthrax Toxin Receptor 1 (ANTXR1) Antibody
Anthrax Toxin Receptor 1 (ANTXR1) Antibody
的详细介绍
ANTXR1 Antibody is a Rabbit Polyclonal antibody against ANTXR1. This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
| Target |
ANTXR1 |
| Reactivity |
Human, Mouse |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IF/ICC |
| Recommended dilutions |
WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human ANTXR1. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 33 kDa/37 kDa/39 kDa/41 kDa/59 kDa/62 kDa
Observed MW: 75 kDa |
| Swiss Prot |
Q9H6X2
|
| GeneID |
84168
|
| Gene Symbol |
ANTXR1 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
