Antigen Peptide Transporter 2 (TAP2) Antibody
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产品名称: Antigen Peptide Transporter 2 (TAP2) Antibody
产品型号: abx117122
产品展商: 其他品牌
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简单介绍
Antigen Peptide Transporter 2 (TAP2) Antibody
Antigen Peptide Transporter 2 (TAP2) Antibody
的详细介绍
TAP2 Antibody is a Rabbit Polyclonal antibody against TAP2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transportersABC proteins transport various molecules across extra- and intra-cellular membranesABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)This protein is a member of the MDR/TAP subfamilyMembers of the MDR/TAP subfamily are involved in multidrug resistanceThis gene is located 7 kb telomeric to gene family member ABCB2The protein encoded by this gene is involved in antigen presentationThis protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulumMutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac diseaseAlternative splicing of this gene produces two products which differ in peptide selectivity and level of restoRation of surface expression of MHC class I molecules.
| Target |
TAP2 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
ELISA, WB, IHC |
| Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human TAP2. |
| Purification |
Affinity Chromatography. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
Q03519
|
| GeneID |
6891
|
| Gene Symbol |
TAP2 |
| Buffer |
PBS, pH7.3, containing 0.02% sodium azide and 50% Glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
