Basigin (CD147) Antibody (PerCP)
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产品名称: Basigin (CD147) Antibody (PerCP)
产品型号: abx200505
产品展商: 其他品牌
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简单介绍
Basigin (CD147) Antibody (PerCP)
的详细介绍
Reacts with basigin or neurothelin, a transmembrane glycoprotein (50-60kd) of the immunoglobulin super-gene family. Neurothelin is a blood brain barrier-specific molecule. It bears homology with mouse gp42 or basigin, human M6 or EmMprin, rat OX-47 or CE-9, and avian HT7 or 5A11. Neurothelin is a molecule which is broadly expressed on cells of hematopoietic and non-hematopoietic origin. Its expression on specific cell types may be regulated by cytokines. CD147 plays a role in embryonal blood-brain barrier development and a role in integrin-mediated adhesion in brain endothelia. Binds to epitope 1 of CD147.
| Target |
CD147 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
FCM |
| Recommended dilutions |
FCM: 20 μl/1 million cells. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Activated HUVEC cells. |
| Purification |
Affinity Chromatography |
| Form |
Liquid |
| Isotype |
IgG1 |
| Conjugation |
PerCP |
| Specificity |
CD147 is a single chain type I transmembrane molecule of 269 amino acids (Miyauchi et al. 1991, Kasinrerk et al. 1992, Biswas et al. 1995): 18 amino acids as secretory signal peptide, 187 residue long extracellular region consists of two Ig-like domains of the C2-type, 24 amino acids of transmembrane region and cytoplasmic region has 40 residues. |
| Storage |
Store in the dark at 2-8 °C. |
| Molecular Weight |
50-65 kDa |
| Swiss Prot |
P35613
|
| GeneID |
682
|
| Buffer |
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 2-3 weeks. |
| Note |
This product is for research use only. |
