Bcl2 Associated X Protein (BAX) Antibody
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产品名称: Bcl2 Associated X Protein (BAX) Antibody
产品型号: abx025467
产品展商: 其他品牌
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简单介绍
Bcl2 Associated X Protein (BAX) Antibody
Bcl2 Associated X Protein (BAX) Antibody
的详细介绍
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero or homodimers and act as anti or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
| Target |
BAX |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Human BAX. |
| Purification |
Purified Mouse Monoclonal Antibody. |
| Isotype |
IgG2b |
| Conjugation |
Unconjugated |
| Specificity |
This BAX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from human BAX. |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
Q07812
|
| Buffer |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
