产品资料
  首页 >>> 产品目录 >>> 试剂盒 >>> Abbexa

BRTC1 / 2 Antibody

如果您对该产品感兴趣的话,可以
产品名称: BRTC1 / 2 Antibody
产品型号: abx034863
产品展商: 其他品牌
产品文档: 无相关文档

简单介绍

BRTC1 / 2 Antibody


BRTC1 / 2 Antibody  的详细介绍
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds to phosphorylated target proteins. SCF (BTRC) mediates the ubiquitination of CTNNB1 and participates in Wnt signaling. SCF (BTRC) mediates the ubiquitination of NFKBIA, NFKBIB and NFKBIE; the degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. Ubiquitination of NFKBIA occurs at 'Lys-21' and 'Lys-22'. SCF (BTRC) mediates the ubiquitination of phosphorylated NFKB1/nuclear factor NF-kappa-B p105 subunit, ATF4, SMAD3, SMAD4, CDC25A, DLG1, FBXO5 and probably NFKB2. SCF (BTRC) mediates the ubiquitination of phosphorylated SNAI1. May be involved in ubiquitination and subsequent proteasomal degradation through a DBB1-CUL4 E3 ubiquitin-protein ligase. Required for activation of NFKB-mediated transcription by IL1B, MAP3K14, MAP3K1, IKBKB and TNF. Required for proteolytic processing of GLI3.

Target BRTC1/2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Immunogen Human BRTC1/2.
Purification Peptide Affinity Purified Rabbit Polyclonal Antibody.
Isotype IgG
Conjugation Unconjugated
Specificity This BRTC1/2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from the N-terminal region of human BRTC1/2.
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot Q9Y297
Gene Symbol BRTC1, BRTC2
NCBI Accession NP_003930.1 NP_378663.1
Buffer PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
相关产品
abbexa 拜力十周年
abbexa 拜力十周年 【abbexa】10th
代理好品Abbexa
abbexa
ABX19211Abbexa
Abbexa Ltd
英国Abbexa
BIOLEAFabbexa 公司代理**试剂盒标准品
BIOLEAFAbbexa Ltd 公司代理**试剂盒标准品
1,4-Alpha-Glucan-Branching Enzyme (GBE1) Antibody abx002344
1-Acylglycerol-3-Phosphate O-Acyltransferase 1 (AGPAT1) Antibody abx230215
1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (AGPAT2) Antibody abx004998
1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (AGPAT2) Antibody abx036556
1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (AGPAT2) Antibody abx321790
1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (AGPAT2) Antibody abx211343
1-Acylglycerol-3-Phosphate O-Acyltransferase 3 (AGPAT3) Antibody abx014067
1-Acylglycerol-3-Phosphate O-Acyltransferase 3 (AGPAT3) Antibody abx036383
1-Acylglycerol-3-Phosphate O-Acyltransferase 3 (AGPAT3) Antibody abx230216
1-Acylglycerol-3-Phosphate O-Acyltransferase 3 (AGPAT3) Antibody abx327851
1-Acylglycerol-3-Phosphate O-Acyltransferase 3 (AGPAT3) Antibody abx330798
1-Acylglycerol-3-Phosphate O-Acyltransferase 3 (AGPAT3) Antibody abx338752
1-Acylglycerol-3-Phosphate O-Acyltransferase 3 (AGPAT3) Antibody (Biotin) abx334451
1-Acylglycerol-3-Phosphate O-Acyltransferase 3 (AGPAT3) Antibody (FITC) abx334450
1-Acylglycerol-3-Phosphate O-Acyltransferase 3 (AGPAT3) Antibody (HRP) abx334449
1-Acylglycerol-3-Phosphate O-Acyltransferase 4 (AGPAT4) Antibody abx034072
1-Acylglycerol-3-Phosphate O-Acyltransferase 4 (AGPAT4) Antibody abx249447
1-Acylglycerol-3-Phosphate O-Acyltransferase 4 (AGPAT4) Antibody abx327852
1-Acylglycerol-3-Phosphate O-Acyltransferase 4 (AGPAT4) Antibody abx241181
1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (AGPAT5) Antibody abx014066
1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (AGPAT5) Antibody abx030540
1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (AGPAT5) Antibody abx338751
1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (AGPAT5) Antibody abx323941
1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (AGPAT5) Antibody abx330799
1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (AGPAT5) Antibody (Biotin) abx334448
1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (AGPAT5) Antibody (FITC) abx334447
1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (AGPAT5) Antibody (HRP) abx334446
1-Acylglycerol-3-Phosphate O-Acyltransferase 7 (AGPAT7) Antibody abx148053
1-Acylglycerol-3-Phosphate O-Acyltransferase 9 Antibody abx110701
1-Aminocyclopropane-1-Carboxylate Synthase-Like Protein 1 (ACCS) Antibody abx003867
1-Aminocyclopropane-1-Carboxylate Synthase-Like Protein 1 (ACCS) Antibody abx029894
1-Aminocyclopropane-1-Carboxylate Synthase-Like Protein 1 (ACCS) Antibody abx110702
1-Aminocyclopropane-1-Carboxylate Synthase-Like Protein 1 (ACCS) Antibody abx006477
14-3-3 Antibody abx230001
14-3-3 Antibody abx230002
14-3-3 Beta (YWHAB) Antibody abx013878
14-3-3 Beta (YWHAB) Antibody abx142316
14-3-3 beta / zeta Antibody abx010303
14-3-3 Beta/alpha (YWHAB) Antibody abx019000
14-3-3 Beta/alpha (YWHAB) Antibody abx019001
14-3-3 Epilson (YWHAE) Antibody abx147641

沪公网安备 31011202007343号