Caspase 9 (CASP9) Antibody
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产品名称: Caspase 9 (CASP9) Antibody
产品型号: abx002046
产品展商: 其他品牌
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简单介绍
Caspase 9 (CASP9) Antibody
的详细介绍
CASP9 Antibody is a Rabbit Polyclonal antibody against CASP9. This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Target |
CASP9 |
Reactivity |
Human, Mouse, Rat |
Host |
Rabbit |
Clonality |
Polyclonal |
Tested Applications |
WB, IHC, IF/ICC |
Recommended dilutions |
WB: 1/200 - 1/500, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Recombinant protein of human CASP9. |
Purification |
Affinity purified. |
Form |
Liquid |
Isotype |
IgG |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
Calculated MW: 17 kDa/30 kDa/36 kDa/46 kDa Observed MW: 46 kDa |
Swiss Prot |
P55211
|
GeneID |
842
|
Gene Symbol |
CASP9 |
Concentration |
> 1 mg/ml |
Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |