Product Name
KCNE2, Blocking Peptide
Full Product Name
KCNE2 Peptide - middle region
Product Gene Name
KCNE2 blocking peptide
[Similar Products]
Product Synonym Gene Name
LQT5; LQT6; ATFB4; MIRP1[Similar Products]
KCNE2 peptide (MBS3246302) is used for blocking the activity of KCNE2 antibody (MBS3221568)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: MVMIGMFSFI IVAILVSTVK SKRREHSNDP YHQYIVEDWQ EKYKSQILNL
3D Structure
ModBase 3D Structure for Q9Y6J6
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of KCNE2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
KCNE2 blocking peptide
This is a synthetic peptide designed for use in combination with anti- KCNE2 Antibody, made
Target Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia.
Product Categories/Family for KCNE2 blocking peptide
Peptide
NCBI/Uniprot data below describe general gene information for KCNE2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_751951.1
[Other Products]
NCBI GenBank Nucleotide #
NM_172201.1
[Other Products]
UniProt Primary Accession #
Q9Y6J6
[Other Products]
UniProt Related Accession #
Q9Y6J6[Other Products]
NCBI Official Full Name
potassium voltage-gated channel subfamily E member 2
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily E regulatory subunit 2
NCBI Official Symbol
KCNE2 [Similar Products]
NCBI Official Synonym Symbols
LQT5; LQT6; ATFB4; MIRP1
[Similar Products]
NCBI Protein Information
potassium voltage-gated channel subfamily E member 2
UniProt Protein Name
Potassium voltage-gated channel subfamily E member 2
UniProt Synonym Protein Names
MinK-related peptide 1; Minimum potassium ion channel-related peptide 1; Potassium channel subunit beta MiRP1
Protein Family
Potassium voltage-gated channel subfamily
UniProt Gene Name
KCNE2 [Similar Products]
UniProt Entry Name
KCNE2_HUMAN
NCBI Summary for KCNE2
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia. [provided by RefSeq, Jul 2008]
Research Articles on KCNE2
1. On the basis of clinical phenotype, the high allelic frequencies of LQT6 mutations in the Exome Aggregation Consortium database, and absence of previous documentation of genotype-phenotype segregation, our findings suggest that many KCNE2 variants, and perhaps all, have been erroneously designated as LQTS-causative mutations. Instead, KCNE2 variants may confer proarrhythmic susceptibility when provoked by additional envir
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
