Full Product Name
5NTC Polyclonal Antibody
Product Synonym Names
Cytosolic purine 5'-nucleotidase; EC 3.1.3.5; Cytosolic 5'-nucleotidase II; NT5C2; NT5B; NT5CP; PNT5
Product Gene Name
anti-5NTC antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P49902
Species Reactivity
Human, Mouse
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-5NTC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-5NTC antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-5NTC antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for 5NTC. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001127845.1
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NCBI GenBank Nucleotide #
NM_001134373.2
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UniProt Primary Accession #
P49902
[Other Products]
UniProt Secondary Accession #
Q5JUV5; B7Z382; D3DR91[Other Products]
UniProt Related Accession #
P49902[Other Products]
NCBI Official Full Name
cytosolic purine 5'-nucleotidase isoform 1
NCBI Official Synonym Full Names
5'-nucleotidase, cytosolic II
NCBI Official Symbol
NT5C2 [Similar Products]
NCBI Official Synonym Symbols
GMP; NT5B; PNT5; SPG45; SPG65; cN-II
[Similar Products]
NCBI Protein Information
cytosolic purine 5'-nucleotidase
UniProt Protein Name
Cytosolic purine 5'-nucleotidase
UniProt Synonym Protein Names
Cytosolic 5'-nucleotidase II
UniProt Gene Name
NT5C2 [Similar Products]
UniProt Synonym Gene Names
NT5B; NT5CP; PNT5 [Similar Products]
NCBI Summary for 5NTC
This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011]
UniProt Comments for 5NTC
May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.
Research Articles on 5NTC
1. Using data from a large-scale genome-wide association study of schizophrenia, study identified several potentially functional variants relating to miRNA function with our top finding being a schizophrenia protective allele that disrupts miR-206s binding to NT5C2 thus leading to increased expression of this gene.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
