Product Name
Caspase (Ice), Recombinant Protein
Full Product Name
Recombinant Drosophila melanogaster Caspase (Ice)
Product Gene Name
Ice recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
29-217aa, Full Length of Mature Protein
Sequence
ALGSVGSGGA GSSGLVAGSS HPYGSGAIGQ LANGYSSPSS SYRKNVAKMV TDRHAAEYNM RHKNRGMALI FNHEHFEVPT LKSRAGTNVD CENLTRVLKQ LDFEVTVYKD CRYKDILRTI EYAASQNHSD SDCILVAILS HGEMGYIYAK DTQYKLDNIW SFFTANHCPS LAGKPKLFFI QACQGDRLD
3D Structure
ModBase 3D Structure for O01382
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Drosophila melanogaster (Fruit fly)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Ice recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Ice. It may not necessarily be applicable to this product.
NCBI Accession #
NP_524551.2
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NCBI GenBank Nucleotide #
NM_079827.3
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UniProt Primary Accession #
O01382
[Other Products]
UniProt Secondary Accession #
Q9VAH1[Other Products]
UniProt Related Accession #
O01382[Other Products]
Molecular Weight
37,363 Da
NCBI Official Full Name
death related ICE-like caspase
NCBI Official Synonym Full Names
Death related ICE-like caspase
NCBI Official Symbol
Drice [Similar Products]
NCBI Official Synonym Symbols
caspase 3; CG7788; crice; DmelCG7788; drice; drIce; drICE; DrIce; DrICE; DRICE; Drive; ice; Ice; ICE
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NCBI Protein Information
CG7788 gene product from transcript CG7788-RA
UniProt Protein Name
Caspase
UniProt Synonym Protein Names
drICE
UniProt Gene Name
Drice [Similar Products]
UniProt Synonym Gene Names
ICE [Similar Products]
UniProt Comments for Ice
Involved in the activation cascade of caspases responsible for apoptosis execution. Acts downstream of rpr. Cleaves baculovirus p35 and lamin DmO in vitro.
Research Articles on Ice
1. Genetic characterization of two gain-of-function alleles of the effector caspase DrICE in Drosophila.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
