Product Name
T2R38, Polyclonal Antibody
Popular Item
Full Product Name
T2R38 Polyclonal Antibody
Product Synonym Names
Taste receptor type 2 member 38; T2R38; PTC bitter taste receptor; Taste receptor type 2 member 61; T2R61; TAS2R38; PTC
Product Gene Name
anti-T2R38 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P59533
Species Reactivity
Human, Mouse, Rat
Specificity
T2R38 Polyclonal Antibody detects endogenous levels of protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Concentration
1mg/ml (lot specific)
Immunogen
Synthesized peptide derived from human protein. at AA range: 180-260
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-T2R38 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-T2R38 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-T2R38 antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for T2R38. It may not necessarily be applicable to this product.
NCBI Accession #
NP_789787.4
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NCBI GenBank Nucleotide #
NM_176817.4
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UniProt Primary Accession #
P59533
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UniProt Secondary Accession #
P59552; Q2M3E8; Q645W3; Q86UK3; A4D1U6[Other Products]
UniProt Related Accession #
P59533[Other Products]
Molecular Weight
Observed band: 36 kDa
NCBI Official Full Name
taste receptor type 2 member 38
NCBI Official Synonym Full Names
taste 2 receptor member 38
NCBI Official Symbol
TAS2R38 [Similar Products]
NCBI Official Synonym Symbols
PTC; T2R38; T2R61
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NCBI Protein Information
taste receptor type 2 member 38
UniProt Protein Name
Taste receptor type 2 member 38
UniProt Synonym Protein Names
PTC bitter taste receptor; Taste receptor type 2 member 61; T2R61
UniProt Gene Name
TAS2R38 [Similar Products]
UniProt Synonym Gene Names
PTC; T2R38; T2R61 [Similar Products]
NCBI Summary for T2R38
This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant). [provided by RefSeq, Oct 2009]
UniProt Comments for T2R38
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 ().
Research Articles on T2R38
1. this study demonstrated that a Bacillus cereus product(s) elicited an NO-mediated innate defense response in upper airway epithelium that seemed to be partially mediated by a T2R signaling pathway
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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