Product Name
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (Agpat1), Recombinant Protein
Popular Item
Full Product Name
Recombinant Mouse 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (Agpat1)
Product Synonym Names
Recombinant 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (Agpat1); 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha EC= 2.3.1.51; 1-acylglycerol-3-phosphate O-acyltransferase 1; 1-AGP acyltransferase 1; 1-AGPAT 1 Lysophosphatidic acid acyltran
Product Gene Name
Agpat1 recombinant protein
[Similar Products]
Product Synonym Gene Name
Agpat1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MELWPGAWTA LLLLLLLLLS TLWFCSSSAK YFFKMAFYNG WILFLAILAI PVCAVRGRNV ENMKILRLLL LHAKYLYGIR VEVRGAHHFP PTQPYVVVSN HQSSLDLLGM MEVLPDRCVP IAKRELLWAG SAGLACWLAG IIFIDRKRTG DAISVMSEVA QTLLTQDVRV WVFPEGTRNH NGSMLPFKRG AFHLAVQAQV PIIPIVMSSY QDFYSKKERR FTSPGRCQVR VLPPVSTEGL TPDDVPALAD SVRHSMLTIF REISTDGLGG GDCLKKPGGA GEARL
Chromosome Location
Chromosome: 17; NC_000083.6 (34605861..34613449). Location: 17 B1; 17 18.18 cM
3D Structure
ModBase 3D Structure for O35083
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mus musculus (Mouse)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Agpat1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Agpat1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001156851.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001163379.1
[Other Products]
UniProt Primary Accession #
O35083
[Other Products]
UniProt Secondary Accession #
O35446[Other Products]
UniProt Related Accession #
O35083[Other Products]
Molecular Weight
31,709 Da[Similar Products]
NCBI Official Full Name
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform 1
NCBI Official Synonym Full Names
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
NCBI Official Symbol
Agpat1 [Similar Products]
NCBI Official Synonym Symbols
1-AGP; 1-AGPAT; AW047140
[Similar Products]
NCBI Protein Information
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; 1-AGPAT 1; Lpaat-alpha; 1-AGP acyltransferase 1; lysophosphatidic acid acyltransferase alpha
UniProt Protein Name
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
UniProt Synonym Protein Names
1-acylglycerol-3-phosphate O-acyltransferase 1; 1-AGP acyltransferase 1; 1-AGPAT 1; Lysophosphatidic acid acyltransferase alpha
Protein Family
1-acyl-sn-glycerol-3-phosphate acyltransferase
UniProt Gene Name
Agpat1 [Similar Products]
UniProt Synonym Gene Names
1-AGP acyltransferase 1; 1-AGPAT 1; LPAAT-alpha [Similar Products]
UniProt Entry Name
PLCA_MOUSE
UniProt Comments for Agpat1
AGPAT1: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
Protein type: Lipid Metabolism - ether lipid; Transferase; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - glycerolipid; Membrane protein, multi-pass; Membrane protein, integral; EC 2.3.1.51
Cellular Component: membrane; endoplasmic reticulum; integral to membrane
Molecular Function: transferase activity; transferase activity, transferring acyl groups; 1-acylglycerol-3-phosphate O-acyltransferase activity
Biological Process: positive regulation of cytokine production; metabolic process; phosphatidic acid biosynthetic process; lipid metabolic process; phospholipid biosynthetic process
Research Articles on Agpat1
1. observations strongly implicate AGPAT1 in the development of skeletal muscle, specifically to terminal differentiation. These findings are linked to the regulation of actin cytoskeleton
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
