Product Name
IL1RAPL1, cDNA Clone
Full Product Name
IL1RAPL1 cDNA Clone
Product Gene Name
IL1RAPL1 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgaaagctc cgattccaca cttgattctc ttatacgcta cttttactca gagtttgaag gttgtgacca aaagaggctc cgccgatgga tgcactgact ggtctatcga tatcaagaaa tatcaagttt tggtgggaga gcctgttcga atcaaatgtg cactctttta tggttatatc agaacaaatt actcccttgc ccaaagtgct ggactcagtt tgatgtggta caaaagttct ggtcctggag actttgaaga gccaatagcc tttgacggaa gtagaatgag caaagaagaa gactccattt ggttccggcc aacattgcta caggacagtg gtctctacgc ctgtgtcatc agaaactcca cttactgtat gaaagtatcc atctcactga cagtgggtga aaatgacact ggactctgct ataattccaa gatgaagtat tttgaaaaag ctgaacttag caaaagcaag gaaatttcat gccgtgacat agaggatttt ctactgccaa ccagagaacc tgaaatcctt tggtacaagg aatgcaggac aaaaacatgg aggccaagta ttgtattcaa aagagatact ctgcttataa gagaagtcag agaagatgac attggaaatt atacctgtga attaaaatat ggaggctttg ttgtgagaag aactactgaa ttaactgtta cagcccctct gactgataag ccacccaagc ttttgtatcc tatggaaagt aaactgacaa ttcaggagac ccagctgggt gactctgcta atctaacctg cagagctttc tttgggtaca gcggagatgt cagtccttta atttactgga tgaaaggaga aaaatttatt gaagatctgg atgaaaatcg agtttgggaa agtgacatta gaattcttaa ggagcatctt ggggaacagg aagtttccat ctcattaatt gtggactctg tggaagaagg tgacttggga aattactcct gttatgttga aaatggaaat ggacgtcgac acgccagcgt tctccttcat aaacgagagc taatgtacac agtggaactt gctggaggcc ttggtgctat actcttgctg cttgtatgtt tggtgaccat ctacaagtgt tacaagatag aaatcatgct cttctacagg aatcattttg gagctgaaga gctcgatgga gacaataaag attatgatgc atacttatca tacaccaaag tggatcctga ccagtggaat caagagactg gggaagaaga acgttttgcc cttgaaatcc tacctgatat gctcgaaaag cattatggat ataagttgtt tataccagat agagatttaa tcccaactgg aacatacatt gaagatgtgg caagatgtgt agatcaaagc aagcggctga ttattgtcat gaccccaaat tacgtagtta gaaggggctg gagcatcttt gagctggaaa ccagacttcg aaatatgctt gtgactggag aaattaaagt gattctaatt gaatgcagtg aactgagagg aattatgaac taccaggagg tggaggccct gaagcacacc atcaagctcc tgacggtcat taaatggcat ggaccaaaat gcaacaagtt gaactccaag ttctggaaac gtttacagta tgaaatgcct tttaagagga tagaacccat tacacatgag caggctttag atgtcagtga gcaagggcct tttggggagc tgcagactgt ctcggccatt tccatggccg cggccacctc cacagctcta gccactgccc atccagatct ccgttctacc tttcacaaca cgtaccattc acaaatgcgt cagaaacact actaccgaag ctatgagtac gacgtacctc ctaccggcac cctgcctctt acctccatag gcaatcagca tacctactgt aacatcccta tgacactcat caacgggcag cggccacaga caaaatcgag cagggagcag aatccagatg aggcccacac aaacagtgcc atcctgccgc tgttgccaag ggagaccagt atatccagtg tgatatggtg a
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of IL1RAPL1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for IL1RAPL1. It may not necessarily be applicable to this product.
NCBI Accession #
BC126345
[Other Products]
UniProt Secondary Accession #
Q9UJ53; A0AVG4[Other Products]
UniProt Related Accession #
Q9NZN1[Other Products]
Molecular Weight
79,969 Da
NCBI Official Full Name
Homo sapiens interleukin 1 receptor accessory protein-like 1, mRNA
NCBI Official Synonym Full Names
interleukin 1 receptor accessory protein like 1
NCBI Official Symbol
IL1RAPL1 [Similar Products]
NCBI Official Synonym Symbols
IL1R8; MRX10; MRX21; MRX34; OPHN4; IL1RAPL; TIGIRR-2
[Similar Products]
NCBI Protein Information
interleukin-1 receptor accessory protein-like 1
UniProt Protein Name
Interleukin-1 receptor accessory protein-like 1
UniProt Synonym Protein Names
Oligophrenin-4; Three immunoglobulin domain-containing IL-1 receptor-related 2; TIGIRR-2; X-linked interleukin-1 receptor accessory protein-like 1
Protein Family
Interleukin-1 receptor accessory protein
UniProt Gene Name
IL1RAPL1 [Similar Products]
UniProt Synonym Gene Names
OPHN4; IL-1-RAPL-1; IL-1RAPL-1; IL1RAPL-1; TIGIRR-2 [Similar Products]
UniProt Entry Name
IRPL1_HUMAN
NCBI Summary for IL1RAPL1
The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities. [provided by RefSeq, Jul 2008]
UniProt Comments for IL1RAPL1
IL1RAPL1: May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in presynaptic and postsynaptic differentiation and dendritic spine formation in neurons. Defects in IL1RAPL1 are the cause of mental retardation X-linked type 21 (MRX21). Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non- syndromic mental retardation patients do not manifest other clinical signs. Belongs to the interleukin-1 receptor family. 1 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.; Membrane protein, integral
Chromosomal Location of Human Ortholog: Xp22.1-p21.3
Cellular Component: cell surface; dendrite; plasma membrane
Molecular Function: interleukin-1 binding; protein binding; receptor binding; voltage-gated calcium channel activity
Biological Process: heterophilic cell adhesion; negative regulation of exocytosis; neuron differentiation; positive regulation of dendrite morphogenesis
Disease: Mental Retardation, X-linked 21
Research Articles on IL1RAPL1
1. It was indicated that a defect in IL1RAPL1 that controls excitatory synapsis formation results in the excitation-inhibition balance affecting various cerebral functions.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
