Product Name
Multiple coagulation factor deficiency protein 2 homolog (Mcfd2), ELISA Kit
Full Product Name
Mouse Multiple coagulation factor deficiency protein 2 homolog ELISA Kit
Product Synonym Names
Multiple coagulation factor deficiency protein 2 homolog; Neural stem cell-derived neuronal survival protein; Mcfd2; Sdnsf
Product Gene Name
Mcfd2 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q8K5B2
Samples
Serum, plasma, tissue homogenates and other
biological fluids.
Detection Range
31.2-2000 pg/mL
Detection Wavelength
450 nm
Preparation and Storage
Store at 4 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of Mcfd2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Mcfd2 purchase
MBS9427464 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Multiple coagulation factor deficiency protein 2 homolog (Mcfd2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Mcfd2. The ELISA analytical biochemical technique of the MBS9427464 kit is based on Mcfd2 antibody-Mcfd2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Mcfd2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Mcfd2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for Mcfd2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_647456.1
[Other Products]
NCBI GenBank Nucleotide #
NM_139295.3
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UniProt Primary Accession #
Q8K5B2
[Other Products]
UniProt Secondary Accession #
Q3U9G5[Other Products]
UniProt Related Accession #
Q8K5B2[Other Products]
Molecular Weight
16,168 Da
NCBI Official Full Name
multiple coagulation factor deficiency protein 2 homolog
NCBI Official Synonym Full Names
multiple coagulation factor deficiency 2
NCBI Official Symbol
Mcfd2 [Similar Products]
NCBI Official Synonym Symbols
F5f8d; Sdnsf; Lman1ip; 1810021C21Rik
[Similar Products]
NCBI Protein Information
multiple coagulation factor deficiency protein 2 homolog
UniProt Protein Name
Multiple coagulation factor deficiency protein 2 homolog
UniProt Synonym Protein Names
Neural stem cell-derived neuronal survival protein
Protein Family
Multiple coagulation factor deficiency protein
UniProt Gene Name
Mcfd2 [Similar Products]
UniProt Synonym Gene Names
Sdnsf [Similar Products]
UniProt Comments for Mcfd2
MCFD2: The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. Plays a role in the secretion of coagulation factors. Defects in MCFD2 are a cause of factor V and factor VIII combined deficiency type 2 (F5F8D2); also known as multiple coagulation factor deficiency 2 (MCFD2). F5F8D2 is a blood coagulation disorder characterized by bleeding symptoms similar to those in hemophilia or parahemophilia, that are caused by single deficiency of FV or FVIII, respectively. The most common symptoms are epistaxis, menorrhagia, and excessive bleeding during or after trauma. Plasma levels of coagulation factors V and VIII are in the range of 5 to 30% of normal. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 17|17 E4
Cellular Component: extracellular region
Biological Process: carboxylic acid metabolic process
Research Articles on Mcfd2
1. These results indicate that increased levels of cargo receptor proteins might have a function either in the quality control of protein folding in the endoplasmic reticulum or in the homeostasis of the intermediate compartment and Golgi complex.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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