Full Product Name
Anti-PRL Mouse mAb
Product Gene Name
anti-PRL antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Form/Format
Purified antibody in PBS with 0.05% sodium azide.
Immunogen
Purified recombinant fragment of human PRL (AA: 65-173) expressed in E Coli.
Other Notes
Small volumes of anti-PRL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PRL antibody
Entrez Summary: This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein.
Applications Tested/Suitable for anti-PRL antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
Western Blot (WB) of anti-PRL antibody
Western blot analysis using PRL mAb against human PRL (AA
Western Blot (WB) of anti-PRL antibody
Western blot analysis using PRL mAb against HEK293 (1) and PRL (AA
Immunofluorescence (IF) of anti-PRL antibody
Immunofluorescence analysis of Hela cells using PRL mouse mAb (green). Blue
Flow Cytometry (FC/FACS) of anti-PRL antibody
Flow cytometric analysis of Hela cells using PRL mouse mAb (green) and negative control (red).
Immunohistochemistry (IHC) of anti-PRL antibody
Immunohistochemical analysis of paraffin-embedded muscle tissues using PRL mouse mAb with DAB staining.
Immunohistochemistry (IHC) of anti-PRL antibody
Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using PRL mouse mAb with DAB staining.
NCBI/Uniprot data below describe general gene information for PRL. It may not necessarily be applicable to this product.
NCBI Accession #
AIZ09172.1
[Other Products]
UniProt Secondary Accession #
Q15199; Q92996[Other Products]
UniProt Related Accession #
P01236[Other Products]
NCBI Official Full Name
PRL, partial
NCBI Official Synonym Full Names
prolactin
NCBI Official Symbol
PRL [Similar Products]
NCBI Official Synonym Symbols
GHA1
[Similar Products]
NCBI Protein Information
prolactin
UniProt Protein Name
Prolactin
UniProt Gene Name
PRL [Similar Products]
UniProt Synonym Gene Names
PRL [Similar Products]
NCBI Summary for PRL
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
UniProt Comments for PRL
prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.
Protein type: Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 6p22.3
Cellular Component: extracellular region
Molecular Function: prolactin receptor binding; protein binding
Biological Process: cell proliferation; cell surface receptor linked signal transduction; cellular protein metabolic process; positive regulation of JAK-STAT cascade; regulation of multicellular organism growth
Research Articles on PRL
1. Data suggest that the serum level of PRL was closely related to the antibody production and disease activity of systemic lupus eruthematosus patients. PRL concentration was dramatically reduced upon the remission of disease activity.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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