ATP dependent RNA helicase SUPV3L1, mitochondrial (SUPV3L1), ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C.

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of SUPV3L1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS7212323 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ATP dependent RNA helicase SUPV3L1, mitochondrial (SUPV3L1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SUPV3L1. The ELISA analytical biochemical technique of the MBS7212323 kit is based on SUPV3L1 antibody-SUPV3L1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SUPV3L1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SUPV3L1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Epigenetics and Nuclear Signaling

87,991 Da

suppressor of var1, 3-like 1 (S. cerevisiae)

ATP-dependent RNA helicase SUPV3L1, mitochondrial; SUV3-like protein 1; suppressor of var1, 3-like 1(SUV3)

ATP-dependent RNA helicase SUPV3L1, mitochondrial

SUV3; SUV3-like protein 1  [Similar Products]

SUV3_HUMAN

SUPV3L1: Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA. Belongs to the helicase family.

Protein type: EC 3.6.4.13; Mitochondrial; DNA-binding; Helicase; RNA-binding

Chromosomal Location of Human Ortholog: 10q22.1

Cellular Component: mitochondrion; mitochondrial matrix; nucleus

Molecular Function: DNA helicase activity; protein binding; protein homodimerization activity; DNA binding; RNA binding; double-stranded RNA binding; helicase activity; ATP-dependent RNA helicase activity; ATP binding

Biological Process: RNA catabolic process; positive regulation of cell growth; DNA duplex unwinding; DNA recombination; negative regulation of apoptosis

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.