Full Product Name
PRL, phosphorylated (S207) (PRL, Prolactin)
Product Synonym Names
Anti -PRL, phosphorylated (S207) (PRL, Prolactin)
Product Gene Name
anti-PRL antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 6; NC_000006.11 (22287473..22303082, complement). Location: 6p22.3
3D Structure
ModBase 3D Structure for P01236
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Immunogen
Phospho-PRL-S207 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 194~223 amino acids surrounding S207 of human PRL.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-PRL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PRL antibody
PRL prolactin acts primarily on the mammary gland by promoting lactation.
Product Categories/Family for anti-PRL antibody
Antibodies; Abs to Hormones, Steroids
Applications Tested/Suitable for anti-PRL antibody
ELISA (EL/EIA), Gel Shift Assay (GS/EMSA)
Application Notes for anti-PRL antibody
Suitable for use in Dot Blot, ELISA
Dilution: ELISA: 1:1,000
Dot blotting 1:100-500
NCBI/Uniprot data below describe general gene information for PRL. It may not necessarily be applicable to this product.
NCBI Accession #
P01236.1
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UniProt Primary Accession #
P01236
[Other Products]
UniProt Secondary Accession #
Q15199; Q92996[Other Products]
UniProt Related Accession #
P01236[Other Products]
Molecular Weight
25,876 Da[Similar Products]
NCBI Official Full Name
Prolactin
NCBI Official Synonym Full Names
prolactin
NCBI Official Symbol
PRL [Similar Products]
NCBI Protein Information
prolactin; decidual prolactin
UniProt Protein Name
Prolactin
UniProt Gene Name
PRL [Similar Products]
UniProt Synonym Gene Names
PRL [Similar Products]
UniProt Entry Name
PRL_HUMAN
NCBI Summary for PRL
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
UniProt Comments for PRL
prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.
Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted; Cytokine
Chromosomal Location of Human Ortholog: 6p22.3
Cellular Component: extracellular region
Molecular Function: protein binding; prolactin receptor binding; hormone activity
Biological Process: lactation; cell proliferation; cell surface receptor linked signal transduction; regulation of multicellular organism growth; positive regulation of JAK-STAT cascade; female pregnancy
Research Articles on PRL
1. High circulating prolactin is associated with subsequent risk of ovarian cancer.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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