Product Name
ATP-dependent RNA helicase SUPV3L1, mitochondrial (SUPV3L1), Recombinant Protein
Full Product Name
Recombinant Human ATP-dependent RNA helicase SUPV3L1, mitochondrial (SUPV3L1)
Product Gene Name
SUPV3L1 recombinant protein
[Similar Products]
Product Synonym Gene Name
SUPV3L1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
23-786aa, Full Length of Mature Protein
Sequence
AICSALRPHF GPFPGVLGQV SVLATASSSA SGGSKIPNTS LFVPLTVKPQ GPSADGDVGA ELTRPLDKNE VKKVLDKFYK RKEIQKLGAD YGLDARLFHQ AFISFRNYIM QSHSLDVDIH IVLNDICFGA AHADDLFPFF LRHAKQIFPV LDCKDDLRKI SDLRIPPNWY PDARAMQRKI IFHSGPTNSG KTYHAIQKYF SAKSGVYCGP LKLLAHEIFE KSNAAGVPCD LVTGEERVTV QPNGKQASHV SCTVEMCSVT TPYEVAVIDE IQMIRDPARG WAWTRALLGL CAEEVHLCGE PAAIDLVMEL MYTTGEEVEV RDYKRLTPIS VLDHALESLD NLRPGDCIVC FSKNDIYSVS RQIEIRGLES AVIYGSLPPG TKLAQAKKFN DPNDPCKILV ATDAIGMGLN LSIRRIIFYS LIKPSINEKG ERELEPITTS QALQIAGRAG RFSSRFKEGE VTTMNHEDLS LLKEILKRPV DPIRAAGLHP TAEQIEMFAY HLPDATLSNL IDIFVDFSQV DGQYFVCNMD DFKFSAELIQ HIPLSLRVRY VFCTAPINKK QPFVCSSLLQ FARQYSRNEP LTFAWLRRYI KWPLLPPKNI KDLMDLEAVH DVLDLYLWLS YRFMDMFPDA SLIRDLQKEL DGIIQDGVHN ITKLIKMSET HKLLNLEGFP SGSQSRLSGT LKSQARRTRG TKALGSKATE PPSPDAGELS LASRLVQQGL LTPDMLKQLE KEWMTQQTEH NKEKTESGTH PKGTRRKKKE PDSD
3D Structure
ModBase 3D Structure for Q8IYB8
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SUPV3L1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SUPV3L1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001288612.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001301683.1
[Other Products]
UniProt Primary Accession #
Q8IYB8
[Other Products]
UniProt Secondary Accession #
O43630; A8K301[Other Products]
UniProt Related Accession #
Q8IYB8[Other Products]
Molecular Weight
87,991 Da
NCBI Official Full Name
ATP-dependent RNA helicase SUPV3L1, mitochondrial isoform 2
NCBI Official Synonym Full Names
Suv3 like RNA helicase
NCBI Official Symbol
SUPV3L1 [Similar Products]
NCBI Official Synonym Symbols
SUV3
[Similar Products]
NCBI Protein Information
ATP-dependent RNA helicase SUPV3L1, mitochondrial
UniProt Protein Name
ATP-dependent RNA helicase SUPV3L1, mitochondrial
UniProt Synonym Protein Names
Suppressor of var1 3-like protein 1; SUV3-like protein 1
Protein Family
ATP-dependent RNA helicase
UniProt Gene Name
SUPV3L1 [Similar Products]
UniProt Synonym Gene Names
SUV3; SUV3-like protein 1 [Similar Products]
UniProt Comments for SUPV3L1
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Research Articles on SUPV3L1
1. the nucleolar- associated human SUV3 protein is an important factor in regulation of the cell cycle.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
