Product Name
(Rhesus macaque) Muscarinic acetylcholine receptor M1 (CHRM1), Recombinant Protein
Popular Item
Full Product Name
Recombinant Macaca mulatta (Rhesus macaque) Muscarinic acetylcholine receptor M1 (CHRM1)
Product Synonym Names
Recombinant (Rhesus macaque) Muscarinic acetylcholine receptor M1 (CHRM1); Muscarinic acetylcholine receptor M1
Product Gene Name
CHRM1 recombinant protein
[Similar Products]
Product Synonym Gene Name
CHRM1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MNTSAPPAVS PNITVLAPGK GPWQVAFIGI TTGLLSLATV TGNLLVLISF KVNTELKTVN NYFLLSLACA DLIIGTFSMN LYTTYLLMGH WALGTLACDL WLALDYVASN ASVMNLLLIS FDRYFSVTRP LSYRAKRTPR RAALMIGLAW LVSFVLWAPA ILFWQYLVGE RTVLAGQCYI QFLSQPIITF GTAMAAFYLP VTVMCTLYWR IYRETENRAR ELAALQGSET PGKGGGSSSS SERSQPGAEG SPETPPGRCC RCCRPPRLLQ AYSWKEDEEE DEGSMESLTS SEGEEPGSEV VIKMPMVDPE AQAPTKQPPR SSPNTVKRPT KKGRDRAGKG QKPRGKEQLA KRKTFSLVKE KKAARTLSAI LLAFILTWTP YNIMVLVSTF CKDCVPETLW ELGYWLCYVN STINPMCYAL CNKAFRDTFR LLLLCRWDKR RWRKIPKRPG SVHRTPSRQC
Chromosome Location
Chromosome: 14; NC_007871.1 (11174905..11176287). Location: chromosome: 14
3D Structure
ModBase 3D Structure for P56489
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Macaca mulatta (Rhesus macaque)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CHRM1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CHRM1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001028117.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001032945.1
[Other Products]
UniProt Primary Accession #
P56489
[Other Products]
UniProt Related Accession #
P56489[Other Products]
Molecular Weight
51,433 Da[Similar Products]
NCBI Official Full Name
muscarinic acetylcholine receptor M1
NCBI Official Symbol
CHRM1 [Similar Products]
NCBI Official Synonym Symbols
M1
[Similar Products]
NCBI Protein Information
muscarinic acetylcholine receptor M1; muscarinic receptor
UniProt Protein Name
Muscarinic acetylcholine receptor M1
Protein Family
Muscarinic acetylcholine receptor
UniProt Gene Name
CHRM1 [Similar Products]
UniProt Entry Name
ACM1_MACMU
UniProt Comments for CHRM1
Function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Subunit structure: Interacts with GPRASP2
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction › synapse › postsynaptic cell membrane; Multi-pass membrane protein.
Sequence similarities: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM1 sub-subfamily.
Research Articles on CHRM1
1. in aged female rhesus monkeys hippocampal M1 receptor function is associated with spatial learning and memory and circadian activity.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.