Product Name
26Rfa, Hypothalamic, Peptide
Full Product Name
26Rfa, Hypothalamic Peptide (Frog)
Product Gene Name
26Rfa peptide
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Val-Gly-Th r-Ala-Leu- Gly-Ser-Le u-Ala-Glu- Glu-Leu-As n-Gly-Tyr- Asn-Arg-Ly s-Lys-Gly- Gly-Phe-Se r-Phe-Arg- Phe-NH2
Purity/Purification
> 95%
Form/Format
Lyophilized powder
Molecular Formula
C127H197N37O36
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Other Notes
Small volumes of 26Rfa peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
26Rfa peptide
Peptide to 26Rfa, Hypothalamic Peptide (Frog)
NCBI/Uniprot data below describe general gene information for 26Rfa. It may not necessarily be applicable to this product.
NCBI Accession #
AAR24354.1
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UniProt Secondary Accession #
Q495K6; A3KFJ6[Other Products]
UniProt Related Accession #
P83859[Other Products]
NCBI Official Full Name
26RFa
NCBI Official Synonym Full Names
pyroglutamylated RFamide peptide
NCBI Official Symbol
QRFP [Similar Products]
NCBI Official Synonym Symbols
P518; 26RFa
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NCBI Protein Information
orexigenic neuropeptide QRFP
UniProt Protein Name
Orexigenic neuropeptide QRFP
UniProt Synonym Protein Names
P518
UniProt Gene Name
QRFP [Similar Products]
UniProt Entry Name
OX26_HUMAN
NCBI Summary for 26Rfa
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. The encoded products are members of the RFamide family of neuropeptides, characterized by their common protein C-terminus consisting of an arginine (R) and an amidated phenylalanine (F). These products include the neuropeptides 26RFa and the N-terminally extended form, 43RFa. Both of these neuropeptides bind to the pyroglutamylated RFamide peptide receptor (QRFPR) and may regulate blood pressure, reproduction and food intake in rodents. [provided by RefSeq, Jul 2015]
UniProt Comments for 26Rfa
QRFP: Stimulates feeding behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland. Belongs to the RFamide neuropeptide family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9q34.12
Cellular Component: extracellular region
Molecular Function: neuropeptide hormone activity; orexigenic neuropeptide QRFP receptor binding
Biological Process: grooming behavior; locomotory behavior; neuropeptide signaling pathway; positive regulation of blood pressure
Research Articles on 26Rfa
1. we show a moderate positive correlation between plasma 26RFa levels and insulin in patients with diabetes. Plasma 26RFa increases in response to glucose tolerance test. 26RFa and its receptor GPR103 are present in human pancreatic beta-cells and gut.
Precautions
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Disclaimer
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