Product Name
Loki/Chk2, Polyclonal Antibody
Full Product Name
Goat anti-Loki/Chk2 (Drosophila melanogaster aa115-128) Antibody
Product Synonym Names
lok; loki; Dme; _CG10895; 10895; 38B.4; CG10895; CHK-2; CHK2; Chk2; DmCHk2; DmChk2; Dmchk2; Dmel\CG10895; Dmnk; Dmnk-L; Dmnk-S; Dmnk/DChk2; LOKI/CHK2; MNK; chk; chk2; chk2/lok; mnk; CG10895-PA; CG10895-PB; CG10895-PC; checkpoint kinase 2; drosophila matern; 10895 antibody; 38B.4 antibody; CG10895 antibody; CG10895-PA antibody; CG10895-PB antibody; CG10895-PC antibody; checkpoint kinase 2 antibody; chk antibody; CHK2 antibody; Chk2 antibody; chk2 antibody; CHK-2 antibody; chk2/lok antibody; DmCHk2 antibody; DmChk2 antibody; Dmchk2 antibody; Dme antibody; Dmel\CG10895 antibody; Dmnk antibody; Dmnk/DChk2 antibody; Dmnk-L antibody; Dmnk-S antibody; drosophila maternal nuclear kinase antibody; localized ovarian kinase antibody; loki antibody; LOKI/CHK2 antibody; lok-PA antibody; lok-PB antibody; lok-PC antibody; maternal nuclear kinase antibody; MNK antibody; mnk antibody; _CG10895 antibody; lok antibody; Loki / Chk2 (Drosophila melanogaster aa115-128)
Product Gene Name
anti-lok antibody
[Similar Products]
Product Synonym Gene Name
Loki; Chk2[Similar Products]
Antibody/Peptide Pairs
Loki / Chk2 peptide (MBS427853) is used for blocking the activity of Loki/Chk2 antibody (MBS422971)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
QDLSRNGTFV NNEK
Species Reactivity
Expected from sequence similarity: Drosophila
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-QDLSRNGTFVNNEK, from the internal region of the protein sequence according to NP_477219.1; NP_477218.1; NP_724241.1.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-lok antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-lok antibody
Peptide ELISA (EIA)
Application Notes for anti-lok antibody
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.
NCBI/Uniprot data below describe general gene information for lok. It may not necessarily be applicable to this product.
NCBI Accession #
NP_477219.1
[Other Products]
NCBI Related Accession #
Manufactured in an ISO 9001:2008 Certified Laboratory.NP_477218.1; NP_724241.1[Other Products]
NCBI GenBank Nucleotide #
NM_057871.4
[Other Products]
UniProt Secondary Accession #
O61268; P91876; Q8SZS3[Other Products]
UniProt Related Accession #
O61267[Other Products]
Molecular Weight
52,346 Da
NCBI Official Full Name
loki, isoform A
NCBI Official Synonym Full Names
loki
NCBI Official Symbol
lok [Similar Products]
NCBI Official Synonym Symbols
10895; 38B.4; CG10895; chk; CHK-2; chk2; Chk2; CHK2; chk2/lok; Dmchk2; DmChk2; DmCHk2; DmelCG10895; Dmnk; Dmnk-L; Dmnk-S; Dmnk/DChk2; LOKI/CHK2; mnk; MNK
[Similar Products]
NCBI Protein Information
CG10895 gene product from transcript CG10895-RA
UniProt Protein Name
Ovarian-specific serine/threonine-protein kinase Lok
UniProt Synonym Protein Names
Protein loki; dMNK
Protein Family
Ovarian-specific serine/threonine-protein kinase
UniProt Gene Name
lok [Similar Products]
UniProt Entry Name
LOK_DROME
UniProt Comments for lok
May have a role in germline establishment.
Research Articles on lok
1. FHA domain in Mnk plays dual functions in mediating embryonic DNA damage responses by means of its phosphopeptide-binding ability: activating Mnk in nucleus upon DNA damage &recruiting Mnk to multiple subcellular structures independently of DNA damage
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.