Product Name
Protein zerknuellt 1 (zen), Recombinant Protein
Full Product Name
Recombinant Drosophila melanogaster Protein zerknuellt 1 (zen)
Product Gene Name
zen recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-353aa, full length protein
Sequence
MSSVMHYYPV HQAKVGSYSA DPSEVKYSDL IYGHHHDVNP IGLPPNYNQM NSNPTTLNDH CSPQHVHQQH VSSDENLPSQ PNHDSQRVKL KRSRTAFTSV QLVELENEFK SNMYLYRTRR IEIAQRLSLC ERQVKIWFQN RRMKFKKDIQ GHREPKSNAK LAQPQAEQSA HRGIVKRLMS YSQDPREGTA AAEKRPMMAV APVNPKPDYQ ASQKMKTEAS TNNGMCSSAD LSEILEHLAQ TTAAPQVSTA TSSTGTSTNS ASSSSSGHYS YNVDLVLQSI KQDLEAAAQA WSKSKSAPIL ATQSWHPSSQ SQVPTSVHAA PSMNLSWGEP AAKSRKLSVN HMNPCVTSYN YPN
3D Structure
ModBase 3D Structure for P09089
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Drosophila melanogaster (Fruit fly)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of zen recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for zen. It may not necessarily be applicable to this product.
NCBI Accession #
NP_476793.1
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NCBI GenBank Nucleotide #
NM_057445.3
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UniProt Primary Accession #
P09089
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UniProt Secondary Accession #
Q0IGS3; Q9VI45[Other Products]
UniProt Related Accession #
P09089[Other Products]
Molecular Weight
39,302 Da
NCBI Official Full Name
zerknullt
NCBI Official Synonym Full Names
zerknullt
NCBI Official Symbol
zen [Similar Products]
NCBI Official Synonym Symbols
BG:DS00276.9; CG1046; dm-zen; DmelCG1046; l(3)84Ad; z1; Zen; ZEN; ZEN VRE; zen1
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NCBI Protein Information
CG1046 gene product from transcript CG1046-RA
UniProt Protein Name
Protein zerknuellt 1
Protein Family
Protein zerknuellt
UniProt Gene Name
zen [Similar Products]
UniProt Synonym Gene Names
z1; zen1; ZEN-1 [Similar Products]
UniProt Comments for zen
Required for the differentiation of the dorsal-ventral pattern, and does not appear to be involved in the process of segmentation.
Research Articles on zen
1. we identify key roles for the Zelda and Zerknullt transcription factors in establishing the resulting expression domain, and find widespread binding of insulator proteins to the Mad and Brinker-bound genomic regions. Analysis of embryos lacking the BEAF-32 insulator protein shows reduced transcription of a peak BMP target gene and a reduction in the number of amnioserosa cells, the fate specified by peak BMP signaling.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
