Product Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1), Protein
Full Product Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Product Synonym Names
Plcg-1; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-gamma-1; PLC-gamma-1
Product Gene Name
PLCG1 protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
27-142aa
3D Structure
ModBase 3D Structure for Q62077
Purity/Purification
>95% by SDS-PAGE
Endotoxin Level
<0.10 EU per 1 mug of the protein by the LAL method
Storage Buffer
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Preparation and Storage
Store at -20 degree C.
Avoid repeated freezing and thawing.
Other Notes
Small volumes of PLCG1 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for PLCG1 protein
ELISA (EIA), Western Blot (WB), Affinity Purification (AP), Protein Array
NCBI/Uniprot data below describe general gene information for PLCG1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_067255.2
[Other Products]
NCBI GenBank Nucleotide #
NM_021280.3
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UniProt Primary Accession #
Q62077
[Other Products]
UniProt Secondary Accession #
Q6P1G1[Other Products]
UniProt Related Accession #
Q62077[Other Products]
Molecular Weight
149,668 Da
NCBI Official Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
NCBI Official Synonym Full Names
phospholipase C, gamma 1
NCBI Official Symbol
Plcg1 [Similar Products]
NCBI Official Synonym Symbols
Cded; Plc-1; Plcg-1; AI894140; Plc-gamma1
[Similar Products]
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
UniProt Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
UniProt Synonym Protein Names
Phosphoinositide phospholipase C-gamma-1; Phospholipase C-gamma-1; PLC-gamma-1
Protein Family
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
UniProt Gene Name
Plcg1 [Similar Products]
UniProt Synonym Gene Names
Plcg-1; PLC-gamma-1 [Similar Products]
UniProt Comments for PLCG1
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Research Articles on PLCG1
1. Smooth muscle PLCgamma1-Akt-mediated Notch1 signaling is crucial for intima formation in vascular injury.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
