1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase eta-2, ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C.

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of PLCH2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2605279 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase eta-2 (PLCH2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PLCH2. The ELISA analytical biochemical technique of the MBS2605279 kit is based on PLCH2 antibody-PLCH2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLCH2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLCH2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

52,942 Da

phospholipase C eta 2

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2

KIAA0450; PLCL4; PLC-L4; Phospholipase C-like protein 4; PLC-eta2  [Similar Products]

PLCH2_HUMAN

PLCH2 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave PtdIns(4,5) P2 to generate second messengers inositol 1,4,5-trisphosphate and diacylglycerol (Zhou et al., 2005 [PubMed 16107206]).[supplied by OMIM, Jun 2009]

PLCL4: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This phospholipase activity is very sensitive to calcium. May be important for formation and maintenance of the neuronal network in the postnatal brain. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.4.11; Phospholipase

Chromosomal Location of Human Ortholog: 1p36.32

Cellular Component: cytoplasm; plasma membrane

Molecular Function: calcium ion binding; phosphoinositide phospholipase C activity; signal transducer activity

Biological Process: inositol phosphate metabolic process; lipid catabolic process; phosphatidylinositol metabolic process

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