Full Product Name
c-Myc Antibody
Product Gene Name
anti-c-Myc antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P01106
Species Reactivity
Human, Mouse, Rat
Form/Format
Purified by peptide affinity column containing 0.5% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.
Other Notes
Small volumes of anti-c-Myc antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-c-Myc antibody
Rabbit polyclonal c-Myc (1) antibody was raised against a 14 amino acid peptide from near the N terminal residues of human c-Myc protein.
Product Categories/Family for anti-c-Myc antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-c-Myc antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-c-Myc antibody
Peptide ELISA: 1:20,000-1:80,000
WB: 1:200-1,000
IHC: 1:50-200
Testing Data of anti-c-Myc antibody
Testing Data of anti-c-Myc antibody
NCBI/Uniprot data below describe general gene information for c-Myc. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002458.2
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NCBI GenBank Nucleotide #
NM_002467.5
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UniProt Primary Accession #
P01106
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UniProt Secondary Accession #
P01107; Q14026; A8WFE7[Other Products]
UniProt Related Accession #
P01106[Other Products]
Molecular Weight
50,565 Da
NCBI Official Full Name
myc proto-oncogene protein isoform 1
NCBI Official Synonym Full Names
MYC proto-oncogene, bHLH transcription factor
NCBI Official Symbol
MYC [Similar Products]
NCBI Official Synonym Symbols
MRTL; MYCC; c-Myc; bHLHe39
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NCBI Protein Information
myc proto-oncogene protein
UniProt Protein Name
Myc proto-oncogene protein
UniProt Synonym Protein Names
Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64
Protein Family
C-Myc-binding protein
UniProt Gene Name
MYC [Similar Products]
UniProt Synonym Gene Names
BHLHE39; bHLHe39 [Similar Products]
NCBI Summary for c-Myc
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
UniProt Comments for c-Myc
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000).
Product References and Citations for anti-c-Myc antibody
(1)Bernstein, P.L., Herrick, D.J., Prokipcak, R.D Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant.Genes Dev. 1992; 6 (4):642-654.
Research Articles on c-Myc
1. mdig directly interacts with c-myc and JAK1 in multiple myeloma (MM) cell lines, which contributes to hyperactivation of the IL-6-JAK-STAT3 signaling important for the pathogenesis of MM.
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